Unfortunately, the cause of lymphoma in dogs is not known. Although several possible causes such as viruses, bacteria, chemical exposure, and physical factors. It is a common cancer in people and dogs, which does not make it any less terrifying for dog owners receiving a canine lymphoma diagnosis. Lymphoma is generally seen in middle aged to older dogs (median age, years). Symptoms- Multicentric lymphoma is the most common type of lymphoma.
Canine Possible Lymphoma of Causes
Dogs with this form of the disease may have signs related to stomach upset, such as vomiting and abdominal pain. When the disease affects most of the intestinal tract, dogs may have devastating signs, such as loss of appetite, vomiting, diarrhea, and continued weight loss because they cannot digest food properly. Mediastinal lymphoma is also uncommon. Dogs with this form of the disease may have an enlarged thymus, lymph nodes, or both.
As the disease advances, signs may include trouble breathing as fluid builds up in the chest and puts pressure on the lungs. The tumor may block the vein that routes blood from the upper part of the body into the heart. In addition to signs related to breathing, some dogs with mediastinal lymphoma pass large amounts of urine and drink more than normal. The medical problems associated with extranodal lymphoma vary and depend on which organ is affected.
Skin lymphoma may appear as single, raised, slow-healing sores or widespread, scaly regions. Signs of lymphoma at other extranodal sites include difficulty breathing lungs , kidney failure kidneys , blindness eyes , seizures central nervous system , and bone fractures and pain bone. These tumors develop slowly, and dogs may not show any signs of the disease.
Canine lymphoma is often relatively easy to diagnose by taking a small sample of tissue or cells from the affected organ system. In dogs with multicentric lymphoma, a needle biopsy of enlarged lymph nodes usually provides enough cells to confirm the diagnosis.
Specialized tests can then help determine the type of lymphoma, which cell types are affected, and the expected outcome. Individual treatment plans vary with respect to the drugs used, dosage, and frequency and duration of treatment. With chemotherapy, the expected survival time for dogs with B-cell lymphoma is about 12 months.
For dogs with T-cell lymphoma, expected survival times are shorter 6 months. Dogs that do not respond to the usual drugs may improve when other treatment plans are used. These alternate plans may include other drugs or radiation. In recent years, treatment has included both initial and longterm medications. Now, similar or improved responses are seen with shorter term therapies, and chemotherapy is often stopped once remission is reached.
Bone marrow transplants may even be an option for some dogs. Although chemotherapy does not cure dogs with lymphoma, in most cases it does extend the length and quality of life.
Keep in mind that these are average values. Each dog is an individual and will respond to treatment differently. In effect, it is a permanent state of remission. While this is a possibility, it is more constructive and realistic to focus on increasing quality of life. It will depend upon how the cancer is behaving, how sick an animal is at the start of treatment, and any abnormalities in organ function especially important are changes in liver and kidney function.
The most effective chemotherapy protocol is a multi-agent chemotherapy; several different drugs vincristine, Cytoxan and Adriamycin are alternated in order to reduce the chance that the tumor cells will become resistant and to reduce the risk of side effects. Other protocols include chemotherapy given once every 2 or 3 weeks either oral or IV , although remission rates and average survival times may be decreased. Most dogs will tolerate chemotherapy well and have minimal side effects.
As a result, the undesirable side-effects normally associated with human chemotherapy are both less common and less severe in animals undergoing chemotherapy.
The most common side-effect is bone marrow suppression, but nausea and anorexia are also occasionally noted. While whiskers are commonly lost, substantial hair loss is not experienced by animals undergoing chemotherapy for cancer. These can include nausea, vomiting, loss of appetite, diarrhea, extreme tiredness or infection.
Adriamycin can cause damage to the heart muscle if given multiple times, though most dogs do not receive enough of this drug to be a concern.
Cytoxan can cause irritation to the bladder wall in a small percentage of dogs. If this occurs, you will see changes in urination blood in the urine, straining to urinate, and frequent urination. Unfortunately, the only way to know whether an animal is going to have a drug reaction is to administer the drug.
Some animals never get sick during chemotherapy, others can be very sensitive to the drugs. If your pet has a serious reaction, the drugs or doses your pet receives will be adjusted with the goal of maintaining a good quality of life. As an owner, you can help your pet with lymphoma by watching him or her closely after each treatment. These infections generally arise from bacteria that normally live in the intestinal tract, respiratory tract, urinary tract, and on the skin not from the environment.
Signs of an infection may include loss of appetite, vomiting, diarrhea, decreased activity, or depression. Call your veterinarian immediately if your pet appears ill while receiving chemotherapy. These signs are usually only brief reactions to the drugs, but prompt treatment can often prevent more serious side effects from developing. The most important aspect of cancer therapy is that you feel as comfortable as possible with your decision. There are no right or wrong answers, and each situation is different.
What is right for one dog and their owner may be unacceptable for another family. If chemotherapy is not an option, either financially, logistically or philosophically, please strongly consider treatment with prednisone. This can significantly improve quality of life, is inexpensive, has few significant side effects, and is an oral medication. Weekly rechecks are not necessary but monthly visits to your regular veterinarian are recommended.
If you have any questions or need help making the best decision for you and your dog, please let us know. Where Does it Hurt? Pain Management in Veterinary Medicine Pain management in animals is recognized as an integral aspect of veterinary practice that offers many advantages to patients. The Breed Golden retrievers are one of the most popular dog breeds in the United States. They were originally bred to aid in retrieving ducks…. Canine Lymphoma This service is available at:
Lymphoma In Dogs: Types, Causes, Symptoms, And Treatments
Multicentric lymphoma is the most common lymphoma in domestic dogs. However, localized The causes of canine lymphoma are not known. However, there. Canine lymphoma or lymphoma-sarcoma is one of the most common cancers in dogs, according to 11motors-club.info Dogs spontaneously. Lymphosarcoma (lymphoma) is a relatively common cancer of lymph cells (called Eighty-five to 90% of all dogs respond to treatment and go into a complete or.