Information about the use of cannabis oil for epilepsy to gain seizure control. Galveston resident Trysten Pearson, who has epilepsy, experienced his first seizure in when he was 12 years old. But last summer, his. I am curious if anyone has tried the new CBD oil to control their epilepsy. I have read many great things about it really controlling seizures and maybe trying it.
for Epilepsy Oil CBD
This type of research is the standard used to determine efficacy of medications. The breadth of applications has also expanded. CBD oils are now available in gels or patches as well as in oil form. Epidiolex, the medication being used in Dr. Sixteen physicians are participating in the study, but none of them are in Colorado. A randomized trial is now occurring to determine the efficacy of this product for children with epilepsy. Any child taking cannabis-related products should be closely monitored by a physician.
Parents of children with severe, intractable epilepsy may understandably be tempted to take desperate measures. The most commonly reported side effects in the Epidiolex study have been drowsiness, diarrhea, and decreased appetite. Increased seizures and convulsions have occurred in a small number of cases.
Long-term effects are an open question. Marijuana use in children has been shown to have negative effects on the brain, but we do not know whether treatments containing little or no THC will have any long-term side effects.
That can be a challenge. No pharmaceutical-grade medical marijuana is available in Colorado. No FDA testing or oversight is required; the FDA has issued warning letters to some producers not in Colorado after testing their products and finding that they did not contain the CBD claimed on the label.
Other growers and dispensaries may also claim to offer forms of marijuana that are high in CBD and low in THC, but parents cannot arrange for their own lab testing in Colorado, because marijuana testing labs are not permitted to test samples from private citizens.
Does medical insurance cover CBD-based products as a treatment for children with epilepsy? As a result, families can expect to pay for it themselves. There is currently no compelling evidence that cannabis oil will help with more common types of epilepsy. Funding was provided by GW Pharmaceuticals.
Despite its potentially misleading headline, the Mail's reporting of the study is accurate and makes clear it relates only to the rarest form of epilepsy. This was a randomised controlled trial RCT aiming to see whether cannabis oil cannabidiol could reduce seizures in people with Lennox—Gastaut syndrome. This is a notoriously hard to treat form of epilepsy and most people with it will need help with day-to-day activities.
The trial was double-blind and with a placebo control, so neither participants nor researchers knew what they were taking. A double-blind RCT is the best way of investigating the effectiveness of a possible new treatment. The size of any benefit would need to outweigh any possible risks to make it a viable treatment.
It recruited people with Lennox—Gastaut syndrome aged from 2 to 55 years who were taking regular antiepileptic drugs and experienced at least 2 drop seizures a week. The main outcome of interest was the number of drop seizures experienced over 28 days. The researchers also looked at other types of seizure and adverse effects. A total of participants were included, who were of average age 15 years and were taking around 3 antiepileptic drugs.
Before the study started, they were experiencing between 80 and 90 drop seizures per month. There was a similar difference with other types of seizure. Side effects such as sleepiness, poor appetite and diarrhoea were common across all groups. In total, 6 patients in the cannabidiol groups and 1 in the placebo group withdrew from the trial because of side effects.
The most common side effect related to cannabidiol was raised liver enzymes. Lennox-Gastaut syndrome is hard to treat and people with it generally have a poor outlook, despite treatment. Seizures are common, and most children have developmental delays. This trial provides evidence that cannabidiol may help improve drop seizures. However, the question is whether this improvement is great enough to make it a feasible and safe treatment.
The study looked at effects on seizure frequency, but it's possible this improvement wouldn't make much difference to the child's development as they grow into adulthood. There is also the important question of the potential harms from this treatment, particularly given its effects on the liver. These may become more marked if treatment was continued in the longer term.
There could also be additional side effects. A new treatment option for this hard-to-treat condition would be welcome, but this would need to be considered by experts in the field.
Again, the media headlines were potentially misleading:
Cannabis oil for epilepsy
Although CBD oil has become a trendy cure-all, treatment of epilepsy is the only use that has garnered significant scientific evidence. A small number of studies have shown that adding cannabis oil to existing medication may be effective in devastating, hard-to-treat epilepsy in. Published in the journal Epilepsy and Behavior, the results indicate use of CBD oil reduced adverse events and seizure severity, in addition to.